Function and Biology Details
Reaction catalysed:
(R)-3-(3,4-dihydroxyphenyl)lactate + NAD(P)(+) = 3-(3,4-dihydroxyphenyl)pyruvate + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Hydroxyphenylpyruvate reductase (preferred)
PDBe Complex ID:
PDB-CPX-179195 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydroxyphenylpyruvate reductase
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 36.34 KDa
Source organism: Plectranthus scutellarioides
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 333 amino acids
Theoretical weight: 36.34 KDa
Source organism: Plectranthus scutellarioides
Expression system: Escherichia coli
UniProt:
- Canonical:
Q65CJ7 (Residues: 1-313; Coverage: 100%)
Sequence domains:
- D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
BESSY BEAMLINE 14.1
Spacegroup:
P3121
Expression system: Escherichia coli
