3tc7

X-ray diffraction
1.5Å resolution

Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62.

Released:

Function and Biology Details

Reaction catalysed:
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-170286 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Indole-3-glycerol phosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 29.8 KDa
Source organism: Saccharolobus solfataricus P2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q06121 (Residues: 1-247; Coverage: 100%)
Gene names: SSO0895, trpC
Sequence domains: Indole-3-glycerol phosphate synthase
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P3121
Unit cell:
a: 60.96Å b: 60.96Å c: 118.663Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.16 0.158 0.193
Expression system: Escherichia coli BL21(DE3)