Function and Biology Details
Reaction catalysed:
(1a) ATP + (R)-lipoate = lipoyl-AMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Lipoate-protein ligase A (preferred)
PDBe Complex ID:
PDB-CPX-190880 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Lipoate-protein ligase A subunit 1
Molecule details ›
Chain: A
Length: 285 amino acids
Theoretical weight: 32.7 KDa
Source organism: Thermoplasma acidophilum DSM 1728
Expression system: Escherichia coli
UniProt:
Sequence domains: Biotin/lipoate A/B protein ligase family
Structure domains: Bira Bifunctional Protein; Domain 2
Length: 285 amino acids
Theoretical weight: 32.7 KDa
Source organism: Thermoplasma acidophilum DSM 1728
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9HKT1 (Residues: 1-262; Coverage: 100%)
Sequence domains: Biotin/lipoate A/B protein ligase family
Structure domains: Bira Bifunctional Protein; Domain 2
Lipoate-protein ligase A subunit 2
Molecule details ›
Chain: C
Length: 91 amino acids
Theoretical weight: 10.56 KDa
Source organism: Thermoplasma acidophilum DSM 1728
Expression system: Escherichia coli
UniProt:
Sequence domains: Bacterial lipoate protein ligase C-terminus
Structure domains: CO dehydrogenase flavoprotein, C-terminal domain
Length: 91 amino acids
Theoretical weight: 10.56 KDa
Source organism: Thermoplasma acidophilum DSM 1728
Expression system: Escherichia coli
UniProt:
- Canonical: Q9HKT2 (Residues: 7-94; Coverage: 94%)
Sequence domains: Bacterial lipoate protein ligase C-terminus
Structure domains: CO dehydrogenase flavoprotein, C-terminal domain
