› 3qps

X-ray diffraction
2.35Å resolution

Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni

Released:
DOI: 10.2210/pdb3qps/pdb
PDB entry 3qps coloured by chain, front view.
PDB entry 3qps coloured by chain, side view.
PDB entry 3qps coloured by chain, top view.
Source organism: Campylobacter jejuni
Primary publication:
Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Lei HT, Shen Z, Surana P, Routh MD, Su CC, Zhang Q, Yu EW
Protein Sci 20 712-23 (2011)
PMID: 21328631

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 25.09 KDa
Source organism: Campylobacter jejuni
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7B8P6 (Residues: 1-210; Coverage: 100%)
Gene names: CmeR, E8P16_04135, E8P16_10565, F8Y55_09710, GNO00_03935, QQI97_001039, cmeR
Sequence domains: Bacterial regulatory proteins, tetR family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CHD 1 x CHD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 93.955Å b: 37.37Å c: 57.792Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.263
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.
Li et al. (2015)
1 more

1 mention without citation

The TetR family of regulators.
Cuthbertson et al. (2013)