3qo0

X-ray diffraction
2.3Å resolution

Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv as IgA

Released:
Source organism: Homo sapiens
Entry authors: Trajtenberg F, Correa-Bove A, Buschiazzo A

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-209311 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 24.01 KDa
Source organism: Homo sapiens
Structure domains: Immunoglobulins
Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN Chain: B
Molecule details ›
Chain: B
Length: 220 amino acids
Theoretical weight: 23.2 KDa
Source organism: Homo sapiens
Structure domains: Immunoglobulins
Tubulin beta chain Chain: C
Molecule details ›
Chain: C
Length: 20 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07437 (Residues: 422-441; Coverage: 5%)
Gene names: OK/SW-cl.56, TUBB, TUBB5

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P21
Unit cell:
a: 53.32Å b: 67.27Å c: 68.88Å
α: 90° β: 103.1° γ: 90°
R-values:
R R work R free
0.171 0.169 0.221
Expression system: Not provided