Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-153247 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth/differentiation factor 5
Molecule details ›
Chains: A, C
Length: 117 amino acids
Theoretical weight: 13.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 117 amino acids
Theoretical weight: 13.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P43026 (Residues: 387-501; Coverage: 24%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Bone morphogenetic protein receptor type-1A
Molecule details ›
Chains: B, D
Length: 135 amino acids
Theoretical weight: 14.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Length: 135 amino acids
Theoretical weight: 14.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P36894 (Residues: 24-152; Coverage: 25%)
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU MICROMAX-007
Expression system: Escherichia coli BL21(DE3)
