› 3q2v

X-ray diffraction
3.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140757 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 550 amino acids
Theoretical weight: 60.93 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P09803 (Residues: 157-700; Coverage: 63%)
Gene name: Cdh1
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

3 bound ligands:
Ligand CA 24 x CA
Ligand MN 2 x MN
Ligand MAN 18 x MAN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 119.14Å b: 79.697Å c: 176.001Å
α: 90° β: 98.56° γ: 90°
R-values:
R R work R free
0.233 0.23 0.293
Expression system: Homo sapiens

Quick links

Citations

59 review citations

The extracellular matrix in tumor progression and metastasis.
Eble et al. (2019)
58 more

46 mentions without citation

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.
Mège et al. (2017)
45 more