› 3q2b

X-ray diffraction
1.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160967 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cofilin/actin-depolymerizing factor homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.9 KDa
Source organism: Plasmodium falciparum HB3
Expression system: Escherichia coli
UniProt:
  • Canonical: P86292 (Residues: 1-122; Coverage: 100%)
Sequence domains: Cofilin/tropomyosin-type actin-binding protein
Structure domains: Severin

Ligands and Environments

2 bound ligands:
Ligand BME 2 x BME
Ligand TAR 2 x TAR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 38.97Å b: 38.97Å c: 142.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.218
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Actin-depolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics.
Poukkula et al. (2011)
7 more

5 mentions without citation

The apicomplexan glideosome and adhesins - Structures and function.
Boucher et al. (2015)
4 more