› 3nul

X-ray diffraction
1.6Å resolution

Profilin I from Arabidopsis thaliana

Released:
DOI: 10.2210/pdb3nul/pdb
PDB entry 3nul coloured by chain, front view.
PDB entry 3nul coloured by chain, side view.
PDB entry 3nul coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
The crystal structure of a major allergen from plants.
Thorn KS, Christensen HE, Shigeta R, Huddler D, Shalaby L, Lindberg U, Chua NH, Schutt CE
Structure 5 19-32 (1997)
PMID: 9016723

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174962 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Profilin-1 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.29 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q42449 (Residues: 2-131; Coverage: 99%)
Gene names: At2g19760, F6F22.21, PFN1, PRF1, PRO1
Sequence domains: Profilin
Structure domains: Dynein light chain 2a, cytoplasmic

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 42.04Å b: 43.07Å c: 59.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.181 0.204
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Profilins as regulators of actin dynamics.
Schlüter et al. (1997)
14 more

16 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
15 more