› 3nsi

X-ray diffraction
2.15Å resolution

Crystal Structure of the Post-Refolded S100A3 Protein Expressed in Insect Cell

Released:
DOI: 10.2210/pdb3nsi/pdb
PDB entry 3nsi coloured by chain, front view.
PDB entry 3nsi coloured by chain, side view.
PDB entry 3nsi coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges.
Unno M, Kawasaki T, Takahara H, Heizmann CW, Kizawa K
J Mol Biol 408 477-90 (2011)
PMID: 21377473

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P33764 (Residues: 1-101; Coverage: 100%)
Gene names: S100A3, S100E
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P31
Unit cell:
a: 58.68Å b: 58.68Å c: 45.763Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.203 0.236
Expression system: Spodoptera frugiperda

Quick links

Citations

4 review citations

Building the niche: the role of the S100 proteins in metastatic growth.
Lukanidin et al. (2012)
3 more

2 mentions without citation

Conservation of Specificity in Two Low-Specificity Proteins.
Wheeler et al. (2018)
1 more