› 3llo

X-ray diffraction
1.57Å resolution

Crystal structure of the STAS domain of motor protein prestin (anion transporter SLC26A5)

Released:
DOI: 10.2210/pdb3llo/pdb
PDB entry 3llo coloured by chain, front view.
PDB entry 3llo coloured by chain, side view.
PDB entry 3llo coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the cytosolic portion of the motor protein prestin and functional role of the STAS domain in SLC26/SulP anion transporters.
Pasqualetto E, Aiello R, Gesiot L, Bonetto G, Bellanda M, Battistutta R
J Mol Biol 400 448-62 (2010)
PMID: 20471983

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prestin Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.77 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9EPH0 (Residues: 505-563, 637-718; Coverage: 19%)
Gene names: Pres, Slc26a5
Sequence domains: STAS domain
Structure domains: STAS domain

Ligands and Environments

1 bound ligand:
Ligand BOG 1 x BOG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3121
Unit cell:
a: 61.59Å b: 61.59Å c: 67.13Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.156 0.154 0.196
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Mechanism and synergism in epithelial fluid and electrolyte secretion.
Hong et al. (2014)
5 more

9 mentions without citation

The SLC26 gene family of anion transporters and channels.
Alper et al. (2013)
8 more