› 3lll

X-ray diffraction
3.3Å resolution

Crystal structure of mouse pacsin2 F-BAR domain

Released:
DOI: 10.2210/pdb3lll/pdb
PDB entry 3lll coloured by chain, front view.
PDB entry 3lll coloured by chain, side view.
PDB entry 3lll coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
Plomann M, Wittmann JG, Rudolph MG
J Mol Biol 400 129-36 (2010)
PMID: 20471395

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194404 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C and casein kinase substrate in neurons protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 34.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WVE8 (Residues: 16-302; Coverage: 59%)
Gene name: Pacsin2
Sequence domains: Fes/CIP4, and EFC/F-BAR homology domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

3 bound ligands:
Ligand CA 2 x CA
Ligand SO4 6 x SO4
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 104.39Å b: 106.4Å c: 125Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.256 0.297
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Membrane curvature at a glance.
McMahon et al. (2015)
9 more

1 mention without citation

Spatial arrangement of proteins in planar and curved membranes by PPM 3.0.
Lomize et al. (2022)