› 3kuz

X-ray diffraction
2.3Å resolution

Crystal structure of the ubiquitin like domain of PLXNC1

Released:
DOI: 10.2210/pdb3kuz/pdb
PDB entry 3kuz coloured by chain, front view.
PDB entry 3kuz coloured by chain, side view.
PDB entry 3kuz coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang H, Li B, Tempel W, Tong Y, Guan X, Zhong N, Crombet L, MacKenzie F, Buck M, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129988 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plexin-C1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 14.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60486 (Residues: 1198-1305; Coverage: 7%)
Gene names: PLXNC1, VESPR
Sequence domains: Plexin cytoplasmic RhoGTPase-binding domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand UNX 12 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 72.246Å b: 72.246Å c: 116.235Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.251 0.25 0.28
Expression system: Escherichia coli

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