› 3ieg

X-ray diffraction
2.51Å resolution

Crystal Structure of P58(IPK) TPR Domain at 2.5 A

Released:
DOI: 10.2210/pdb3ieg/pdb
PDB entry 3ieg coloured by chain, front view.
PDB entry 3ieg coloured by chain, side view.
PDB entry 3ieg coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR.
Tao J, Petrova K, Ron D, Sha B
J Mol Biol 397 1307-15 (2010)
PMID: 20184891

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187618 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DnaJ homolog subfamily C member 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 359 amino acids
Theoretical weight: 41.38 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q91YW3 (Residues: 35-393; Coverage: 76%)
Gene names: Dnajc3, P58ipk
Sequence domains:
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 84.041Å b: 93.186Å c: 84.412Å
α: 90° β: 119.5° γ: 90°
R-values:
R R work R free
0.247 0.245 0.284
Expression system: Escherichia coli

Quick links

Citations

4 review citations

How Do J-Proteins Get Hsp70 to Do So Many Different Things?
Craig et al. (2017)
3 more

6 mentions without citation

Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR.
Tao et al. (2010)
5 more