› 3hrw

X-ray diffraction
2.8Å resolution

Crystal structure of hemoglobin from mouse (Mus musculus)at 2.8

Released:
DOI: 10.2210/pdb3hrw/pdb
PDB entry 3hrw coloured by chain, front view.
PDB entry 3hrw coloured by chain, side view.
PDB entry 3hrw coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of hemoglobin from mouse (Mus musculus) compared with those from other small animals and humans.
Sundaresan SS, Ramesh P, Shobana N, Vinuchakkaravarthy T, Yasien S, Ponnuswamy MNG
Acta Crystallogr F Struct Biol Commun 77 113-120 (2021)
PMID: 33830076

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135374 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 14.98 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01942 (Residues: 2-142; Coverage: 99%)
Gene names: Hba, Hba-a1
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta-1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 15.73 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P02088 (Residues: 2-147; Coverage: 99%)
Gene name: Hbb-b1
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 4 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P212121
Unit cell:
a: 53.081Å b: 65.94Å c: 150.931Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.243 0.306

Quick links

Citations

1 review citation

X-ray crystallography and sickle cell disease drug discovery-a tribute to Donald Abraham.
Donkor et al. (2023)

9 mentions without citation

Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.
Heremans et al. (2022)
8 more