› 3hq6

X-ray diffraction
2Å resolution

Cytochrome c peroxidase from G. sulfurreducens, wild type

Released:
DOI: 10.2210/pdb3hq6/pdb
PDB entry 3hq6 coloured by chain, front view.
PDB entry 3hq6 coloured by chain, side view.
PDB entry 3hq6 coloured by chain, top view.
Source organism: Geobacter sulfurreducens
Primary publication:
CcpA from Geobacter sulfurreducens is a basic di-heme cytochrome c peroxidase.
Hoffmann M, Seidel J, Einsle O
J Mol Biol 393 951-65 (2009)
PMID: 19735665

Function and Biology Details

Reaction catalysed: 
2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181021 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 345 amino acids
Theoretical weight: 36.93 KDa
Source organism: Geobacter sulfurreducens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q749D0 (Residues: 1-345; Coverage: 100%)
Gene names: GSU2813, ccpA
Sequence domains:
Structure domains: Cytochrome c-like domain

Ligands and Environments


Cofactor: Ligand HEM 4 x HEM
1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P1
Unit cell:
a: 54.241Å b: 55.783Å c: 78.644Å
α: 68.69° β: 71.84° γ: 57.76°
R-values:
R R work R free
0.193 0.189 0.266
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Multi-heme proteins: nature's electronic multi-purpose tool.
Bewley et al. (2013)
4 more

4 mentions without citation

Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface.
Siglioccolo et al. (2011)
3 more