› 3hko

X-ray diffraction
1.8Å resolution

Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40

Released:
DOI: 10.2210/pdb3hko/pdb
PDB entry 3hko coloured by chain, front view.
PDB entry 3hko coloured by chain, side view.
PDB entry 3hko coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Wernimont AK, Hutchinson A, Wasney G, Vedadi M, MacKenzie F, Kozieradzki I, Cossar D, Weigelt J, Edwards AM, Arrowsmith CH, Bountra C, Botchkarev A, Hui R, Artz JD, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176956 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
non-specific serine/threonine protein kinase Chain: A
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 39.6 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CZ29 (Residues: 126-452; Coverage: 40%)
Gene name: cgd7_40
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand GOL 1 x GOL
Ligand ZN 1 x ZN
Ligand ANP 1 x ANP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 54.48Å b: 63.045Å c: 84.041Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.246
Expression system: Escherichia coli

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