› 3hhv

X-ray diffraction
1.83Å resolution

The crystal structure of the Thioredoxin A2 from Sulfolobus solfataricus

Released:
DOI: 10.2210/pdb3hhv/pdb
PDB entry 3hhv coloured by chain, front view.
PDB entry 3hhv coloured by chain, side view.
PDB entry 3hhv coloured by chain, top view.
Source organism: Saccharolobus solfataricus
Primary publication:
The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability.
Ruggiero A, Masullo M, Marasco D, Ruocco MR, Grimaldi P, Arcari P, Zagari A, Vitagliano L
Proteins 77 1004-8 (2009)
PMID: 19768676

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189016 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.64 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q97WI4 (Residues: 26-135; Coverage: 82%)
Gene names: SSO2232, trxA-2
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P2
Unit cell:
a: 28.272Å b: 27.882Å c: 62.06Å
α: 90° β: 92.34° γ: 90°
R-values:
R R work R free
0.199 0.196 0.246
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

Phase-dependent generation and transmission of time information by the KaiABC circadian clock oscillator through SasA-KaiC interaction in cyanobacteria.
Valencia S et al. (2012)
3 more

2 mentions without citation

Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases.
Premkumar et al. (2013)
1 more