› 3gng

X-ray diffraction
3Å resolution

P21B crystal structure of R1-R7 of Murine MVP

Released:
DOI: 10.2210/pdb3gng/pdb
PDB entry 3gng coloured by chain, front view.
PDB entry 3gng coloured by chain, side view.
PDB entry 3gng coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP.
Querol-Audí J, Casañas A, Usón I, Luque D, Castón JR, Fita I, Verdaguer N
EMBO J 28 3450-7 (2009)
PMID: 19779459

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major vault protein Chain: A
Molecule details ›
Chain: A
Length: 387 amino acids
Theoretical weight: 43.74 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9EQK5 (Residues: 1-383; Coverage: 45%)
Gene name: Mvp
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 58.776Å b: 60.087Å c: 68.628Å
α: 90° β: 95.34° γ: 90°
R-values:
R R work R free
0.258 0.257 0.287
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Nanocaged platforms: modification, drug delivery and nanotoxicity. Opening synthetic cages to release the tiger.
Karimi et al. (2017)
5 more

1 mention without citation

The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP.
Querol-Audí et al. (2009)