› 3gj0

X-ray diffraction
1.48Å resolution

Crystal structure of human RanGDP

Released:
DOI: 10.2210/pdb3gj0/pdb
PDB entry 3gj0 coloured by chain, front view.
PDB entry 3gj0 coloured by chain, side view.
PDB entry 3gj0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic and biochemical analysis of the Ran-binding zinc finger domain.
Partridge JR, Schwartz TU
J Mol Biol 391 375-89 (2009)
PMID: 19505478

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTP-binding nuclear protein Ran Chains: A, B
Molecule details ›
Chains: A, B
Length: 221 amino acids
Theoretical weight: 24.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62826 (Residues: 2-216; Coverage: 100%)
Gene names: ARA24, OK/SW-cl.81, RAN
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand GDP 2 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 81.544Å b: 81.544Å c: 130.567Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.203
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The structure of the nuclear pore complex.
Hoelz et al. (2011)
4 more

14 mentions without citation

Ran-dependent nuclear export mediators: a structural perspective.
Güttler et al. (2011)
13 more