3fkc

X-ray diffraction
1.7Å resolution

Crystal Structure of Human Zinc finger and BTB domain containing 33

Released:
Source organism: Homo sapiens
Entry authors: Filippakopoulos P, Bullock A, Keates T, Burgess-Brown N, Muniz J, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-183158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulator Kaiso Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 13.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86T24 (Residues: 1-116; Coverage: 17%)
Gene names: KAISO, ZBTB33, ZNF348
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P6222
Unit cell:
a: 118.358Å b: 118.358Å c: 38.981Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.176 0.195
Expression system: Escherichia coli