› 3fhh

X-ray diffraction
2.6Å resolution

Crystal structure of the heme/hemoglobin outer membrane transporter ShuA from Shigella dysenteriae

Released:
DOI: 10.2210/pdb3fhh/pdb
PDB entry 3fhh coloured by chain, front view.
PDB entry 3fhh coloured by chain, side view.
PDB entry 3fhh coloured by chain, top view.
Source organism: Shigella dysenteriae
Primary publication:
Structure of the heme/hemoglobin outer membrane receptor ShuA from Shigella dysenteriae: heme binding by an induced fit mechanism.
Cobessi D, Meksem A, Brillet K
Proteins 78 286-94 (2010)
PMID: 19731368

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane heme/hemoglobin receptor Chain: A
Molecule details ›
Chain: A
Length: 640 amino acids
Theoretical weight: 70.57 KDa
Source organism: Shigella dysenteriae
Expression system: Escherichia coli
UniProt:
  • Canonical: P72412 (Residues: 29-660; Coverage: 100%)
Gene names: NCTC4837_05545, shuA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand BOG 1 x BOG
Ligand PB 4 x PB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 78.099Å b: 114.217Å c: 117.085Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.237 0.286
Expression system: Escherichia coli

Quick links

Citations

6 review citations

TonB or not TonB: is that the question?
Krewulak et al. (2011)
5 more

11 mentions without citation

TonB-dependent transporters: regulation, structure, and function.
Noinaj et al. (2010)
10 more