› 3e4u

X-ray diffraction
2.1Å resolution

Crystal Structure of the Wild-Type Human BCL6 BTB/POZ Domain

Released:
DOI: 10.2210/pdb3e4u/pdb
PDB entry 3e4u coloured by chain, front view.
PDB entry 3e4u coloured by chain, side view.
PDB entry 3e4u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the wild-type human BCL6 POZ domain.
Stead MA, Rosbrook GO, Hadden JM, Trinh CH, Carr SB, Wright SC
Acta Crystallogr Sect F Struct Biol Cryst Commun 64 1101-4 (2008)
PMID: 19052359

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154263 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell lymphoma 6 protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 130 amino acids
Theoretical weight: 14.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P41182 (Residues: 5-129; Coverage: 18%)
Gene names: BCL5, BCL6, LAZ3, ZBTB27, ZNF51
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P32
Unit cell:
a: 59.209Å b: 59.209Å c: 158.971Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.219 0.259
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.
Rosbrook et al. (2012)
2 more

2 mentions without citation

Structure of the wild-type human BCL6 POZ domain.
Stead et al. (2008)
1 more