3cmo

X-ray diffraction
2.3Å resolution

HIV neutralizing monoclonal antibody YZ18

Released:
Source organism: Mus musculus
Entry authors: Jin L, Prasad V, Paul S

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
PDBe Complex ID:
PDB-CPX-212396 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab light chain Chains: L, X
Molecule details ›
Chains: L, X
Length: 210 amino acids
Theoretical weight: 23.26 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: H, Y
Molecule details ›
Chains: H, Y
Length: 222 amino acids
Theoretical weight: 23.94 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q6PJA7 (Residues: 21-241; Coverage: 49%)
Gene name: Igh
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 75.65Å b: 69.94Å c: 84.36Å
α: 90° β: 94.93° γ: 90°
R-values:
R R work R free
0.248 0.248 0.287