› 3beh

X-ray diffraction
3.1Å resolution

Structure of a Bacterial Cyclic Nucleotide Regulated Ion Channel

Released:
DOI: 10.2210/pdb3beh/pdb
PDB entry 3beh coloured by chain, front view.
PDB entry 3beh coloured by chain, side view.
PDB entry 3beh coloured by chain, top view.
Source organism: Mesorhizobium loti
Primary publication:
Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel.
Clayton GM, Altieri S, Heginbotham L, Unger VM, Morais-Cabral JH
Proc Natl Acad Sci U S A 105 1511-5 (2008)
PMID: 18216238

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic nucleotide-gated potassium channel mll3241 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 355 amino acids
Theoretical weight: 37.77 KDa
Source organism: Mesorhizobium loti
Expression system: Escherichia coli
UniProt:
  • Canonical: Q98GN8 (Residues: 1-355; Coverage: 100%)
Gene name: mll3241
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand K 5 x K
Ligand LDA 4 x LDA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: R3
Unit cell:
a: 282.73Å b: 282.73Å c: 105.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.276 0.276 0.286
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Sensing voltage across lipid membranes.
Swartz KJ. (2008)
14 more

38 mentions without citation

Structural correlates of selectivity and inactivation in potassium channels.
McCoy et al. (2012)
37 more