3bbp

X-ray diffraction
3Å resolution

Rab6-GTP:GCC185 Rab binding domain complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer (preferred)
homo dimer
monomeric
PDBe Complex ID:
PDB-CPX-148956 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-6A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 211 amino acids
Theoretical weight: 23.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20340 (Residues: 1-206; Coverage: 99%)
Gene names: RAB6, RAB6A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
GRIP and coiled-coil domain-containing protein 2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 71 amino acids
Theoretical weight: 8.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8IWJ2 (Residues: 1547-1612; Coverage: 4%)
Gene names: GCC2, KIAA0336, RANBP2L4
Sequence domains: Rab binding domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1, SSRL BEAMLINE BL11-1
Spacegroup: P6422
Unit cell:
a: 168.599Å b: 168.599Å c: 168.955Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.268
Expression system: Escherichia coli BL21(DE3)