› 3b6v

X-ray diffraction
2.7Å resolution

Crystal structure of the motor domain of human kinesin family member 3C in complex with ADP

Released:
DOI: 10.2210/pdb3b6v/pdb
PDB entry 3b6v coloured by chain, front view.
PDB entry 3b6v coloured by chain, side view.
PDB entry 3b6v coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhu H, Tempel W, Shen Y, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127133 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF3C Chains: A, B
Molecule details ›
Chains: A, B
Length: 395 amino acids
Theoretical weight: 43.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14782 (Residues: 7-383; Coverage: 48%)
Gene name: KIF3C
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

3 bound ligands:
Ligand MG 2 x MG
Ligand ADP 2 x ADP
Ligand UNX 8 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 135.739Å b: 47.588Å c: 116.951Å
α: 90° β: 103.16° γ: 90°
R-values:
R R work R free
0.205 0.202 0.274
Expression system: Escherichia coli

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