› 2zwh

Fiber diffraction
3.3Å resolution

Model for the F-actin structure

Released:
DOI: 10.2210/pdb2zwh/pdb
PDB entry 2zwh coloured by chain, front view.
PDB entry 2zwh coloured by chain, side view.
PDB entry 2zwh coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
The nature of the globular- to fibrous-actin transition.
Oda T, Iwasa M, Aihara T, Maéda Y, Narita A
Nature 457 441-5 (2009)
PMID: 19158791

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ADP 1 x ADP
Ligand CA 1 x CA
1 modified residue:
Ligand HIC 1 x HIC

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU, SPRING-8 BEAMLINE BL40B2, SPRING-8 BEAMLINE BL45XU
R-values:
R R work R free
0.143 not available not available

Quick links

Citations

62 review citations

Actin structure and function.
Dominguez et al. (2011)
61 more

57 mentions without citation

The actin gene family: function follows isoform.
Perrin et al. (2010)
56 more