› 2zl5

X-ray diffraction
1.47Å resolution

Atomic resolution structural characterization of recognition of histo-blood group antigen by Norwalk virus

Released:
DOI: 10.2210/pdb2zl5/pdb
PDB entry 2zl5 coloured by chain, front view.
PDB entry 2zl5 coloured by chain, side view.
PDB entry 2zl5 coloured by chain, top view.
Source organism: Norwalk virus
Primary publication:
Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus.
Choi JM, Hutson AM, Estes MK, Prasad BV
Proc Natl Acad Sci U S A 105 9175-80 (2008)
PMID: 18599458

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182861 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble capsid protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 295 amino acids
Theoretical weight: 31.57 KDa
Source organism: Norwalk virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q83884 (Residues: 225-519; Coverage: 56%)
Gene name: ORF2
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CA 2 x CA
Ligand ACT 3 x ACT
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3121
Unit cell:
a: 83.517Å b: 83.517Å c: 163.368Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.181 0.2
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

47 review citations

Biological roles of glycans.
Varki A. (2017)
46 more

9 mentions without citation

Structural basis of glycan interaction in gastroenteric viral pathogens.
Venkataram Prasad et al. (2014)
8 more