Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181992 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Crossover junction endonuclease MUS81
Molecule details ›
Chain: A
Length: 311 amino acids
Theoretical weight: 35.01 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Crossover junction endonuclease EME1, DNA-binding domain
Length: 311 amino acids
Theoretical weight: 35.01 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q7SXA9 (Residues: 295-604; Coverage: 51%)
Sequence domains:
Structure domains: Crossover junction endonuclease EME1, DNA-binding domain
Crossover junction endonuclease EME1
Molecule details ›
Chain: B
Length: 341 amino acids
Theoretical weight: 37.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 341 amino acids
Theoretical weight: 37.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q96AY2 (Residues: 246-570; Coverage: 57%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 4A
Spacegroup:
P3121
Expression system: Escherichia coli BL21(DE3)
