› 2ys2

Solution NMR

Solution structure of the BTK motif of human Cytoplasmic tyrosine-protein kinase BMX

Released:
DOI: 10.2210/pdb2ys2/pdb
PDB entry 2ys2 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ys2 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ys2 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Abe H, Tochio N, Tomizawa T, Koshiba S, Yoneyama M, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic tyrosine-protein kinase BMX Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.16 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P51813 (Residues: 113-149; Coverage: 6%)
Gene name: BMX
Sequence domains: BTK motif

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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