› 2ypy

X-ray diffraction
2.45Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181196 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein LANA1-like DNA-binding domain-containing protein Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 139 amino acids
Theoretical weight: 15.76 KDa
Source organism: Human herpesvirus 8 type M
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q76SB0 (Residues: 1013-1149; Coverage: 12%)
Sequence domains: Protein LANA1-like, DNA-binding domain
Structure domains: Epstein Barr virus nuclear antigen-1, DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand CL 24 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 51.74Å b: 175.92Å c: 97.58Å
α: 90° β: 95.5° γ: 90°
R-values:
R R work R free
0.222 0.221 0.252
Expression system: Escherichia coli BL21(DE3)

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Citations

16 review citations

Kaposi sarcoma-associated herpesvirus: immunobiology, oncogenesis, and therapy.
Dittmer et al. (2016)
15 more

4 mentions without citation

A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.
Hellert et al. (2013)
3 more