› 2yoq

X-ray diffraction
2.35Å resolution

Structure of FAM3B PANDER E30 construct

Released:
DOI: 10.2210/pdb2yoq/pdb
PDB entry 2yoq coloured by chain, front view.
PDB entry 2yoq coloured by chain, side view.
PDB entry 2yoq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold.
Johansson P, Bernström J, Gorman T, Oster L, Bäckström S, Schweikart F, Xu B, Xue Y, Schiavone LH
Structure 21 306-13 (2013)
PMID: 23333428

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein FAM3B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 214 amino acids
Theoretical weight: 23.97 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9D309 (Residues: 30-235; Coverage: 100%)
Gene names: Fam3b, ORF9
Sequence domains: Interleukin-like EMT inducer

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P31
Unit cell:
a: 86.54Å b: 86.54Å c: 96.28Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.16 0.158 0.19
Expression system: Homo sapiens

Quick links

Citations

12 citation in other articles

ILEI: a novel marker for epithelial-mesenchymal transition and poor prognosis in colorectal cancer.
Gao et al. (2014)
11 more

2 mentions without citation

Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan.
Kuwabara et al. (2016)
1 more