› 2ylh

X-ray diffraction
1.7Å resolution

Structure of N-terminal domain of Candida albicans Als9-2 G299W mutant

Released:
DOI: 10.2210/pdb2ylh/pdb
PDB entry 2ylh coloured by chain, front view.
PDB entry 2ylh coloured by chain, side view.
PDB entry 2ylh coloured by chain, top view.
Source organism: Candida albicans
Primary publication:
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans.
Salgado PS, Yan R, Taylor JD, Burchell L, Jones R, Hoyer LL, Matthews SJ, Simpson PJ, Cota E
Proc Natl Acad Sci U S A 108 15775-9 (2011)
PMID: 21896717

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Agglutinin-like protein 9 Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 33.68 KDa
Source organism: Candida albicans
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A0A1D8PQ86 (Residues: 18-328; Coverage: 17%)
Gene names: ALS11, ALS9, CAALFM_C603710WA, orf19.13164, orf19.5742
Sequence domains: Cell-wall agglutinin N-terminal ligand-sugar binding
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 35.2Å b: 68.7Å c: 121.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.237
Expression system: Escherichia coli BL21

Quick links

Citations

15 review citations

Development and regulation of single- and multi-species Candida albicans biofilms.
Lohse et al. (2018)
14 more

2 mentions without citation

Adhesins of Yeasts: Protein Structure and Interactions.
Willaert RG. (2018)
1 more