Function and Biology Details
Reactions catalysed:
Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- DNA methylase, N-6 adenine-specific, conserved site
- DNA methylase, adenine-specific
- N6 adenine-specific DNA methyltransferase, N-terminal domain
- Type I restriction enzyme EcoKI-like, methylase subunit, N-terminal domain superfamily
- Type I restriction modification DNA specificity domain
- Type I restriction modification DNA specificity domain superfamily
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
Type I restriction enzyme EcoKI and DNA (preferred)
PDBe Complex ID:
PDB-CPX-115949 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
Type I restriction enzyme EcoKI specificity subunit
Molecule details ›
Chain: A
Length: 464 amino acids
Theoretical weight: 51.47 KDa
Source organism: Escherichia coli
UniProt:
Sequence domains: Type I restriction modification DNA specificity domain
Length: 464 amino acids
Theoretical weight: 51.47 KDa
Source organism: Escherichia coli
UniProt:
- Canonical:
P05719 (Residues: 1-464; Coverage: 100%)
Sequence domains: Type I restriction modification DNA specificity domain
Type I restriction enzyme EcoKI methylase subunit
Molecule details ›
