› 2xzg

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169454 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Clathrin heavy chain 1 Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 40.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00610 (Residues: 1-364; Coverage: 22%)
Gene names: CLH17, CLTC, CLTCL2, KIAA0034
Sequence domains:
Structure domains: Clathrin heavy-chain terminal domain

Ligands and Environments

4 bound ligands:
Ligand PEG 2 x PEG
Ligand GOL 1 x GOL
Ligand ACT 1 x ACT
Ligand VH1 1 x VH1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 71.34Å b: 73.915Å c: 84.384Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.159 0.2
Expression system: Escherichia coli

Quick links

Citations

49 review citations

The cell biology of receptor-mediated virus entry.
Grove et al. (2011)
48 more

8 mentions without citation

Getting in touch with the clathrin terminal domain.
Lemmon et al. (2012)
7 more