› 2xyc

X-ray diffraction
2.51Å resolution

CRYSTAL STRUCTURE OF NCAM2 IGIV-FN3I

Released:
DOI: 10.2210/pdb2xyc/pdb
PDB entry 2xyc coloured by chain, front view.
PDB entry 2xyc coloured by chain, side view.
PDB entry 2xyc coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.
Kulahin N, Kristensen O, Rasmussen KK, Olsen L, Rydberg P, Vestergaard B, Kastrup JS, Berezin V, Bock E, Walmod PS, Gajhede M
Structure 19 203-11 (2011)
PMID: 21300289

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 2 Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 32.51 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: O15394 (Residues: 301-591; Coverage: 36%)
Gene names: NCAM2, NCAM21
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand NAG 3 x NAG
Ligand EPE 1 x EPE
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-5
Spacegroup: P43212
Unit cell:
a: 139.66Å b: 139.66Å c: 47.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.241
Expression system: Komagataella pastoris

Quick links

Citations

6 review citations

Polysialic acid: biosynthesis, novel functions and applications.
Colley et al. (2014)
5 more

2 mentions without citation

Calcium binding by the PKD1 domain regulates interdomain flexibility in Vibrio cholerae metalloprotease PrtV.
Edwin et al. (2013)
1 more