› 2wt1

X-ray diffraction
1.9Å resolution

Galectin domain of porcine adenovirus type 4 NADC-1 isolate fibre complexed with lacto-N-neo-tetraose

Released:
DOI: 10.2210/pdb2wt1/pdb
PDB entry 2wt1 coloured by chain, front view.
PDB entry 2wt1 coloured by chain, side view.
PDB entry 2wt1 coloured by chain, top view.
Source organism: Porcine adenovirus 4
Primary publication:
Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.
Guardado-Calvo P, Muñoz EM, Llamas-Saiz AL, Fox GC, Kahn R, Curiel DT, Glasgow JN, van Raaij MJ
J Virol 84 10558-68 (2010)
PMID: 20686025

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182793 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 37.91 KDa
Source organism: Porcine adenovirus 4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q83467 (Residues: 393-703; Coverage: 44%)
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL, NAG
Carbohydrate polymer
1 bound ligand:
Ligand NO3 3 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2
Unit cell:
a: 95.42Å b: 38.79Å c: 84.4Å
α: 90° β: 102.2° γ: 90°
R-values:
R R work R free
0.189 0.188 0.223
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Latest insights on adenovirus structure and assembly.
San Martín C. (2012)
2 more

2 mentions without citation

Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.
Guardado-Calvo et al. (2010)
1 more