› 2wla

X-ray diffraction
2Å resolution

Streptococcus pyogenes Dpr

Released:
DOI: 10.2210/pdb2wla/pdb
PDB entry 2wla coloured by chain, front view.
PDB entry 2wla coloured by chain, side view.
PDB entry 2wla coloured by chain, top view.
Source organism: Streptococcus pyogenes
Primary publication:
Crystal structures of Streptococcus pyogenes Dpr reveal a dodecameric iron-binding protein with a ferroxidase site.
Haikarainen T, Tsou CC, Wu JJ, Papageorgiou AC
J Biol Inorg Chem 15 183-94 (2010)
PMID: 19727858

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189420 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin/DPS protein domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 19.34 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99YU7 (Residues: 1-175; Coverage: 100%)
Gene names: SPy_1531, dpr
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: F4132
Unit cell:
a: 189.268Å b: 189.268Å c: 189.268Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.153 0.182
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Dps biomineralizing proteins: multifunctional architects of nature.
Zeth K. (2012)
2 more

1 mention without citation

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites.
Ansell et al. (2015)