› 2sn3

X-ray diffraction
1.2Å resolution

STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb2sn3/pdb
PDB entry 2sn3 coloured by chain, front view.
PDB entry 2sn3 coloured by chain, side view.
PDB entry 2sn3 coloured by chain, top view.
Source organism: Centruroides exilicauda
Primary publication:
Structure of scorpion toxin variant-3 at 1.2 A resolution.
Zhao B, Carson M, Ealick SE, Bugg CE
J Mol Biol 227 239-52 (1992)
PMID: 1522588

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin CsEv3 Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.1 KDa
Source organism: Centruroides exilicauda
Expression system: Not provided
UniProt:
  • Canonical: P01494 (Residues: 20-84; Coverage: 96%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

1 bound ligand:
Ligand MPD 1 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 52.07Å b: 41.94Å c: 28.32Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 not available not available
Expression system: Not provided

Quick links

Citations

3 review citations

Scorpion toxins specific for Na+-channels.
Possani et al. (1999)
2 more

6 mentions without citation

A graph-theory algorithm for rapid protein side-chain prediction.
Canutescu et al. (2003)
5 more