› 2rv5

Solution NMR

Solution structures of the DNA-binding domain (ZF8) of mouse immune-related zinc-finger protein ZFAT

Released:
DOI: 10.2210/pdb2rv5/pdb
PDB entry 2rv5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rv5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rv5 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT.
Tochio N, Umehara T, Nakabayashi K, Yoneyama M, Tsuda K, Shirouzu M, Koshiba S, Watanabe S, Kigawa T, Sasazuki T, Shirasawa S, Yokoyama S
J Struct Funct Genomics 16 55-65 (2015)
PMID: 25801860

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182024 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein ZFAT Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 3.71 KDa
Source organism: Mus musculus
Expression system: CELL-FREE SYNTHESIS
UniProt:
  • Canonical: Q7TS63 (Residues: 458-485; Coverage: 2%)
Gene names: Gm922, Zfat, Zfat1, Zfp406, Znf406

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: CELL-FREE SYNTHESIS

Quick links

Citations

2 review citations

Zinc finger structure determination by NMR: Why zinc fingers can be a handful.
Neuhaus D. (2022)
1 more

2 mentions without citation

Chiral hydroxylation at the mononuclear nonheme Fe(II) center of 4-(S) hydroxymandelate synthase--a structure-activity relationship analysis.
Di Giuro et al. (2013)
1 more