› 2rmh

Solution NMR

Human Urocortin 3

Released:
DOI: 10.2210/pdb2rmh/pdb
PDB entry 2rmh coloured by chain, ensemble of 20 models, front view.
PDB entry 2rmh coloured by chain, ensemble of 20 models, side view.
PDB entry 2rmh coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Common and divergent structural features of a series of corticotropin releasing factor-related peptides.
Grace CR, Perrin MH, Cantle JP, Vale WW, Rivier JE, Riek R
J Am Chem Soc 129 16102-14 (2007)
PMID: 18052377

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188330 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Urocortin-3 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.14 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q969E3 (Residues: 120-157; Coverage: 27%)
Gene names: SPC, UCN3
Sequence domains: Corticotropin-releasing factor family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

18 review citations

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
Parthier et al. (2009)
17 more

2 mentions without citation

Early engineering approaches to improve peptide developability and manufacturability.
Furman et al. (2015)
1 more