› 2q4q

X-ray diffraction
2.59Å resolution

Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.95870

Released:
DOI: 10.2210/pdb2q4q/pdb
PDB entry 2q4q coloured by chain, ensemble of 16 models, front view.
PDB entry 2q4q coloured by chain, ensemble of 16 models, side view.
PDB entry 2q4q coloured by chain, ensemble of 16 models, top view.
Source organism: Homo sapiens
Primary publication:
Ensemble refinement of protein crystal structures: validation and application.
Levin EJ, Kondrashov DA, Wesenberg GE, Phillips GN
Structure 15 1040-52 (2007)
PMID: 17850744

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190661 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mth938 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 122 amino acids
Theoretical weight: 13.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H7C9 (Residues: 2-122; Coverage: 99%)
Gene names: AAMDC, C11orf67, PTD015
Sequence domains: Protein of unknown function (DUF498/DUF598)
Structure domains: MTH938-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 45.912Å b: 57.731Å c: 89.195Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.173 0.267
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Enzymes in jasmonate biosynthesis - structure, function, regulation.
Schaller et al. (2009)
18 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)