2n8m

Solution NMR

Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target

Released:
Entry authors: Nicastro G, Ramos A, Candel A, Hollingworth D

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-128803 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Insulin-like growth factor 2 mRNA-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 20.61 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: O42254 (Residues: 387-573; Coverage: 33%)
Gene names: IGF2BP1, VICKZ1, ZBP1
Sequence domains: KH domain
Structure domains: TATA-Binding Protein
RNA (5'-R(P*UP*CP*GP*GP*AP*CP*U)-3') Chain: B
Molecule details ›
Chain: B
Length: 7 nucleotides
Theoretical weight: 2.2 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 58%
Refinement method: torsion angle dynamics
Expression systems:
  • Escherichia coli
  • Not provided