› 2n5r

Solution NMR

NMR structure of cFLIP-derived calmodulin binding peptide

Released:
DOI: 10.2210/pdb2n5r/pdb
PDB entry 2n5r coloured by chain, ensemble of 21 models, front view.
PDB entry 2n5r coloured by chain, ensemble of 21 models, side view.
PDB entry 2n5r coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
Identification and Characterization of the Interaction Site between cFLIPL and Calmodulin.
Gaidos G, Panaitiu AE, Guo B, Pellegrini M, Mierke DF
PLoS One 10 e0141692 (2015)
PMID: 26529318

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127505 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CASP8 and FADD-like apoptosis regulator subunit p43 Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.56 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O15519 (Residues: 62-73; Coverage: 3%)
Gene names: CASH, CASP8AP1, CFLAR, CLARP, MRIT

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 35%
Refinement method: distance geometry
Expression system: Not provided

Quick links

Citations

1 citations in other articles

An engineered construct of cFLIP provides insight into DED1 structure and interactions.
Panaitiu et al. (2022)

1 mention without citation

Identification and Characterization of the Interaction Site between cFLIPL and Calmodulin.
Gaidos et al. (2015)