› 2n16

Solution NMR

Solution structure of G-quadruplex recognition domain of RHAU

Released:
DOI: 10.2210/pdb2n16/pdb
PDB entry 2n16 coloured by chain, ensemble of 10 models, front view.
PDB entry 2n16 coloured by chain, ensemble of 10 models, side view.
PDB entry 2n16 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex.
Heddi B, Cheong VV, Martadinata H, Phan AT
Proc Natl Acad Sci U S A 112 9608-13 (2015)
PMID: 26195789

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190557 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent DNA/RNA helicase DHX36 Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H2U1 (Residues: 53-70; Coverage: 2%)
Gene names: DDX36, DHX36, KIAA1488, MLEL1, RHAU

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Expression system: Escherichia coli

Quick links

Citations

18 review citations

RNA G-quadruplexes and their potential regulatory roles in translation.
Song et al. (2016)
17 more

1 mention without citation

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex.
Heddi et al. (2015)