› 2mzk

Solution NMR

The solution structure of the Magnesium-bound Conantokin RLB

Released:
DOI: 10.2210/pdb2mzk/pdb
PDB entry 2mzk coloured by chain, ensemble of 10 models, front view.
PDB entry 2mzk coloured by chain, ensemble of 10 models, side view.
PDB entry 2mzk coloured by chain, ensemble of 10 models, top view.
Source organism: Conus rolani
Primary publication:
Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
Kunda S, Yuan Y, Balsara RD, Zajicek J, Castellino FJ
J Biol Chem 290 18156-18172 (2015)
PMID: 26048991

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143625 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Conantokin Rl-B Chain: A
Molecule details ›
Chain: A
Length: 19 amino acids
Theoretical weight: 2.24 KDa
Source organism: Conus rolani
Expression system: Not provided
UniProt:
  • Canonical: P0DKZ0 (Residues: 79-96; Coverage: 24%)

Ligands and Environments

No bound ligands
2 modified residues:
Ligand CGU 5 x CGU
Ligand HYP 1 x HYP

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Protective treatments and their target retinal ganglion cells in diabetic retinopathy.
Zhang et al. (2017)
1 more

1 mention without citation

Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
Kunda et al. (2015)