› 2muq

Solution NMR

Solution Structure of the Human FAAP20 UBZ

Released:
DOI: 10.2210/pdb2muq/pdb
PDB entry 2muq coloured by chain, ensemble of 10 models, front view.
PDB entry 2muq coloured by chain, ensemble of 10 models, side view.
PDB entry 2muq coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.
Wojtaszek JL, Wang S, Kim H, Wu Q, D'Andrea AD, Zhou P
Nucleic Acids Res 42 13997-4005 (2014)
PMID: 25414354

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180089 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fanconi anemia core complex-associated protein 20 Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 4.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6NZ36 (Residues: 140-180; Coverage: 23%)
Gene names: C1orf86, FAAP20, FP7162
Sequence domains: Ubiquitin-binding zinc-finger

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Wojtaszek et al. (2019)
7 more

1 mention without citation

Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.
Wojtaszek et al. (2014)