› 2moa

Solution NMR

Solution NMR structure of peptide ImI1 (peak 2)

Released:
DOI: 10.2210/pdb2moa/pdb
PDB entry 2moa coloured by chain, ensemble of 20 models, front view.
PDB entry 2moa coloured by chain, ensemble of 20 models, side view.
PDB entry 2moa coloured by chain, ensemble of 20 models, top view.
Source organism: Conus imperialis
Primary publication:
Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Chen S, Gopalakrishnan R, Schaer T, Marger F, Hovius R, Bertrand D, Pojer F, Heinis C
Nat Chem 6 1009-16 (2014)
PMID: 25343607

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156277 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin ImI Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.38 KDa
Source organism: Conus imperialis
Expression system: Not provided
UniProt:
  • Canonical: P50983 (Residues: 5-16; Coverage: 71%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 45%
Refinement method: simulated annealing, molecular dynamics
Expression system: Not provided

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Citations

10 review citations

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.
Pelay-Gimeno et al. (2015)
9 more