Function and Biology Details
Reaction catalysed:
L-tyrosine + tetrahydrobiopterin + O(2) = L-dopa + 4a-hydroxytetrahydrobiopterin
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Tyrosine 3-monooxygenase (preferred)
PDBe Complex ID:
PDB-CPX-137482 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
41%
Refinement method:
simulated annealing
Expression system: Escherichia coli